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East Genomics

Prenatal testing

Routine prenatal genetic testing and some disease-specific testing is delivered by the East GLH Laboratories at Cambridge, Nottingham and Leicester.

The pathway for all prenatal testing is through the appropriate local laboratory at Cambridge, Leicester or Nottingham. Tests for certain specialist clinical indications are delivered by our partner GLHs across England.

Samples should be sent to the local laboratory for DNA preparation and routine testing. Where specialist testing is required, DNA samples will then be transferred to the designated GLH. All enquiries should be directed to us, as your local GLH via geneticslaboratories@nhs.net. Please add ‘PRENATAL’ to the subject field of emails.

To facilitate rapid prenatal testing for familial variants, please download and complete the new prenatal notification form (below) and send in advance of the procedure to the local laboratory with as much notice as possible. This will ensure that the testing GLH has all the necessary information and samples to expediate a rapid report.

Red cell disorder testing

The North West GLH (Manchester) is the designated centre for East GLH referrals for this test. As per the standard pathway, all prenatal samples should be sent to the local laboratory for DNA preparation, routine testing and rapid transfer to the North West GLH.

Molecular prenatal notification form

Use this form to notify the East GLH Genomic Laboratories of planned prenatal testing for molecular testing.

Download WORD – CUH Molecular Prenatal Test Notification Form
Download PDF – CUH Molecular Prenatal Test Notification Form

Send completed documents and copies of relevant genetic reports to us at geneticslaboratories@nhs.net (please include ‘prenatal test’ in the subject heading).

Non-invasive prenatal testing (NIPT)

All maternity providers across England are now offering non-invasive prenatal testing (NIPT) as part of the existing NHS screening pathway for Down’s syndrome, Edwards’ syndrome and Patau’s syndrome.

Further information

Screening pathway

NIPT request forms

Rapid exome sequencing (R21)

Test R21 is a rapid exome sequencing service for testing for fetal anomalies with a likely monogenic disorder.